335 research outputs found

    Generalized Sum Pooling for Metric Learning

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    A common architectural choice for deep metric learning is a convolutional neural network followed by global average pooling (GAP). Albeit simple, GAP is a highly effective way to aggregate information. One possible explanation for the effectiveness of GAP is considering each feature vector as representing a different semantic entity and GAP as a convex combination of them. Following this perspective, we generalize GAP and propose a learnable generalized sum pooling method (GSP). GSP improves GAP with two distinct abilities: i) the ability to choose a subset of semantic entities, effectively learning to ignore nuisance information, and ii) learning the weights corresponding to the importance of each entity. Formally, we propose an entropy-smoothed optimal transport problem and show that it is a strict generalization of GAP, i.e., a specific realization of the problem gives back GAP. We show that this optimization problem enjoys analytical gradients enabling us to use it as a direct learnable replacement for GAP. We further propose a zero-shot loss to ease the learning of GSP. We show the effectiveness of our method with extensive evaluations on 4 popular metric learning benchmarks. Code is available at: GSP-DML FrameworkComment: Accepted as a conference paper at International Conference on Computer Vision (ICCV) 202

    Individual-level determinants of depressive symptoms and associated diseases history in Turkish persons aged 15 years and older: A population-based study

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    BackgroundDepressive symptoms are associated with both long-lasting and short-term repetitive mood disorders and affect a person's ability to function and lead a rewarding life. In addition to predisposing genetic causes, other factors such as socioeconomic and demographic factors, and chronic diseases have also been reported to associate with depression. In this study, we analyzed the association between history of chronic diseases and presentation of depressive symptoms amongst Turkish individuals. MethodsWe employed the 2019 Turkey health survey to analyze data of 11,993 individuals aged 15+ years. Depressive symptoms were assessed using the eight-item Patient Health Questionnaire (PHQ-8) coded with a binary measure, a score of 10 as moderate-severely depressed. A number of sociodemographic characteristics were adjusted for in the analyses. Logistic regression models were used to test the association between chronic diseases and depressive symptoms in the study sample. ResultsOur analysis revealed that 6.24% of the 11,993 participants had reported an episode of depressive symptoms. The prevalence of depressive symptoms in men was 1.85% and in women, it was 2.34 times higher. Participants who had previously reported experiencing coronary heart diseases (AOR = 7.79, 95% CI [4.96-12.23]), urinary incontinences (AOR = 7.90, 95% CI [4.93-12.66]), and liver cirrhosis (AOR = 7.50, 95% CI [4.90-10.42]) were approximately eight times likely to have depressive symptoms. Similarly, participants with Alzheimer's disease (AOR = 6.83, 95% CI [5.11-8.42]), kidney problems (AOR = 6.63, 95% CI [4.05-10.85]), and history of allergies (AOR = 6.35, 95% CI [4.28-9.23]) had approximately seven-fold odds of reporting episodes of depressive symptoms. The odds of presenting with depressive symptoms amongst participants aged >= 50 were higher than in individuals aged <= 49 years. ConclusionAt individual level, gender and general health status were associated with increased odds of depression. Furthermore, a history of any of the chronic diseases, irrespective of age, was a positive predictor of depression in our study population. Our findings could help to serve as a reference for monitoring depression amongst individuals with chronic conditions, planning health resources and developing preventive and screening strategies targeting those exposed to predisposing factors

    Effects of salicylic acid on wheat salt sensitivity

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    Salicylic acid (SA), a plant phenolic compound, is now considered as a hormone-like endogenous regulator, and there is a great interest to clarify its role in the defence mechanisms against biotic and abiotic stressors. In this study, investigations on the effects of foliar-applied SA on salt sensitivity, hydrogen peroxide (H2O2) generation and activities of antioxidant enzymes like peroxidase (POX) and catalase (CAT) in plant tissues under salt stress was performed. SA treatment significantly increased the fresh and dry weights in both root and shoots of wheat plants under salt stress. Similarly, POX and CAT activities were also augmented by SA treatment. While the highest POX activity was recorded at SA+120 mM NaCl, CAT activity also exhibited an increase compared to salt treatment without SA. In parallel to increasing antioxidative activity, SA treatment decreased H2O2 content when compared to plants growing under salt stress without SA. The results revealed that salt-induced deleterious effect in wheat seedlings were significantly alleviated by the SA treatment. SA can be used as a signal molecule to investigate plant defense to abiotic stress. After the application of SA, increasing tolerance of wheat seedlings to salt stress may be related to increases in antioxidative enzyme activitiy.Key words: Wheat, salicylic acid, antioxidative enzyme activities, peroxidase (POX), catalase (CAT), hydrogen peroxide (H2O2) content

    Biofortification and Localization of Zinc in Wheat Grain

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    Zinc (Zn) deficiency associated with low dietary intake is a well-documented public health problem, resulting in serious health and socioeconomic problems. Field experiments were conducted with wheat to test the role of both soil and foliar application of ZnSO4 in Zn concentration of whole grain and grain fractions (e.g., bran, embryo and endosperm) in 3 locations. Foliar application of ZnSO4 was realized at different growth stages (e.g., stem elongation, boot, milk, dough stages) to study the effect of timing of foliar Zn application on grain Zn concentration. The rate of foliar Zn application at each growth stage was 4 kg of ZnSO4 3 7H2O ha-1. Laser ablation (LA)-ICP-MS was used to follow the localization of Zn within grain. Soil Zn application at a rate of 50 kg of ZnSO4 3 7H2O ha-1 was effective in increasing grain Zn concentration in the Zn-deficient location, but not in the locations without soil Zn deficiency. In all locations, foliar application of Zn significantly increased Zn concentration in whole grain and in each grain fraction, particularly in the case of high soil N fertilization. In Zn-deficient location, grain Zn concentration increased from 11 mg kg-1 to 22 mg kg-1 with foliar Zn application and to 27 mg kg-1 with a combined application of ZnSO4 to soil and foliar. In locations without soil Zn deficiency, combination of high N application with two times foliar Zn application (e.g., at the booting and milk stages) increased grain Zn concentration, on average, from 28 mg kg-1 to 58 mg kg-1. Both ICP-OES and LA-ICP-MS data showed that the increase in Zn concentration of whole grain and grain fractions was pronounced when Zn was sprayed at the late growth stage (e.g., milk and dough). LA-ICP-MS data also indicated that Zn was transported into endosperm through the crease phloem. To our knowledge, this is the first study to show that the timing of foliar Zn application is of great importance in increasing grain Zn in wheat, especially in the endosperm part that is the predominant grain fraction consumed in many countries. Providing a large pool of Zn in vegetative tissues during the grain filling (e.g., via foliar Zn spray) is an important practice to increase grain Zn and contribute to human nutritio

    Capital Fixity and Mobility in Response to the 2008-09 Crisis: Variegated Neoliberalism in Mexico and Turkey

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    The article examines the 2008-9 crisis responses in Mexico and Turkey as examples of variegated neoliberalism. The simultaneous interests of corporations and banks relative to the national fixing of capital and their mobility in the form of global investment heavily influenced each state authority’s policy responses to the crisis at the expense of the interests of the poor, workers, and peasantry. Rather than pitching this as either evidence of persistent national differentiation or some Keynesian state resurgence, we argue from a historical materialist geographical framework that the responses of capital and state authorities in Mexico and Turkey actively constitute and reconstitute the global parameters of market regulatory design and neoliberal class rule through each state’s distinct domestic policy formation and crisis management processes. While differing in specific content the form of Mexico and Turkey’s state responses to the crisis ensured continuity in their foregoing neoliberal strategies of development and capital accumulation, most notably in the continued oppression of workers. That is, the prevailing strategy of accumulation continues to be variegated neoliberalism

    Performance comparison of CVD grown carbon nanofiber based on single- and multi-layer graphene oxides in melt-compounded PA6.6 nanocomposites

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    In the present study, newly design hybrid nanostructures were produced by growing long carbon nanofibers (CNF) on single- and multi-layer graphene oxide (GO) sheets in the presence of catalyst by chemical vapor deposition (CVD). Chemical composition analysis indicated the formation of Fe-C bonds by the deposition of carbon atoms on catalyst surface of Fe2O3 and increasing in C/O atomic ratio confirming CNF growing. These hybrid additives were distributed homogeneously through polyamide 6.6 (PA6.6) chains by high shear thermokinetic mixer in melt phase. Spectroscopic studies showed that the differences in the number of graphene layer in hybrid structures directly affected the crystalline behavior and dispersion state in polymer matrix. Flexural strength and flexural modulus of PA6.6 nanocomposites were improved up to 14.7% and 14% by the integration of 0.5 wt% CNF grown on multi-layer GO, respectively, whereas there was a significant loss in flexural properties of single-layer GO based nanocomposites. Also, the integration of 0.5 wt% multi-layer GO hybrid reinforcement in PA6.6 provided a significant increase in tensile modulus about 24%. Therefore, multi-layer GO with CNF increased the degree of crystallinity in nanocomposites by forming intercalated structure and acted as a nucleating agent causing the improvement in mechanical properties

    The walls of gated communities in Brazil and Turkey: security, separation or status?

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    Gated communities are common types of housing estates found in many countries. They are based on strictly controlled access of people. Houses, and at times high-rise apartment blocks, are built behind a common wall, along private internal streets. Both in Brazil and in Turkey these types of residential neighborhoods can be found mainly on the outskirts of large urban areas. This paper investigates the reasons for the increase of such residential areas, in relation to the two countries urban problems. In Brazil the dominant reason for the proliferation of gated communities, found in the literature and in advertisement of such estates, is security, in view of the countries high crime rates. In Turkey the main reason for a family to choose to live in such residential areas is status and privacy. Although Brazil and Turkey have very different cultural backgrounds, in both countries gated communities are increasingly popular. The attraction of these so-called communities must therefore be analyzed. Are people more vulnerable in large mega-cities? Also, the impact on urban prospects as a whole must be discussed. Socio-cultural and psychological concepts such as territoriality, security, privacy, which can be represented by a pattern of behavior of an individual or group, as based on control of space, are thus touched on in the paper. Conclusions confirm that the reasons for preferences for gated communities are the feeling of belonging to a special place, fear of crime and a sense security and determine decision making of families in their homeownership choices

    Turner syndrome and associated problems in turkish children: A multicenter study

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    Objective: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls. This study aimed to systematically investigate the key clinical features of TS in relationship to karyotype in a large pediatric Turkish patient population. Methods: Our retrospective study included 842 karyotype-proven TS patients aged 0-18 years who were evaluated in 35 different centers in Turkey in the years 2013-2014. Results: The most common karyotype was 45,X (50.7%), followed by 45,X/46,XX (10.8%), 46,X,i(Xq) (10.1%) and 45,X/46,X,i(Xq) (9.5%). Mean age at diagnosis was 10.2±4.4 years. The most common presenting complaints were short stature and delayed puberty. Among patients diagnosed before age one year, the ratio of karyotype 45,X was significantly higher than that of other karyotype groups. Cardiac defects (bicuspid aortic valve, coarctation of the aorta and aortic stenosi) were the most common congenital anomalies, occurring in 25% of the TS cases. This was followed by urinary system anomalies (horseshoe kidney, double collector duct system and renal rotation) detected in 16.3%. Hashimoto’s thyroiditis was found in 11.1% of patients, gastrointestinal abnormalities in 8.9%, ear nose and throat problems in 22.6%, dermatologic problems in 21.8% and osteoporosis in 15.3%. Learning difficulties and/or psychosocial problems were encountered in 39.1%. Insulin resistance and impaired fasting glucose were detected in 3.4% and 2.2%, respectively. Dyslipidemia prevalence was 11.4%. Conclusion: This comprehensive study systematically evaluated the largest group of karyotype-proven TS girls to date. The karyotype distribution, congenital anomaly and comorbidity profile closely parallel that from other countries and support the need for close medical surveillance of these complex patients throughout their lifespan. © Journal of Clinical Research in Pediatric Endocrinology
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